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On the page
Cell Molecular Biology
Biology
Cell biology is signified by the study and evaluation of the structure and interactions of cellular components. In molecular biology, molecular or chemical aspects of biological processes are studied. Cell biology targets the compartmentalization of cells, while molecular biology aims to detail the chemistry of the biological processes in the various compartments. For example, cell biology has identified the ribosome as the sub-cellular site for protein synthesis, and molecular biology accounts for the chemical transformations involved.
The research topic also includes various aspects of immunology, exemplified by studies of endocytosis mediated by the innate immune system.
Various ailments and disorders can be detected and monitored by identification of specific biomarkers, and hence, methods to recognize, capture, and quantify important biomarkers are developed and validated. Biological barriers, skin and mucous membranes, maintain the integrity of the individual, and the central features of the barriers are extensively studied using complex model barriers.
Core methodologies include cell culture, flow cytometry, microscopy, electrophoresis, and PCR
Researchers, publications and projects
Sebastian Björklund
Rita Del Giudice
Petri Gudmundsson
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2024 | Article in journal
Lipid exchange of apolipoprotein A-I amyloidogenic variants in reconstituted high-density lipoprotein with artificial membranes
Yubexi Correa, Mathilde Ravel, Marie Imbert, Sarah Waldie, Luke Clifton, Ann Terry, Felix Roosen-Runge, Jens O. Lagerstedt, Michael Moir, Tamim Darwish, Marité Cárdenas, Rita Del Giudice
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2024 | Article in journal
RNA sequencing unravels novel L cell constituents and mechanisms of GLP-1 secretion in human gastric bypass-operated intestine
Michael G Miskelly, Andreas Lindqvist, Elena Piccinin, Alexander Hamilton, Elaine Cowan, Bent-Johnny Nergård, Rita Del Giudice, Mtakai Ngara, Luis R Cataldo, Dmytro Kryvokhyzha, Petr Volkov, Luke Engelking, Isabella Artner, Jens O Lagerstedt, Lena Eliasson, Emma Ahlqvist, Antonio Moschetta, Jan Hedenbro, Nils Wierup
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2023 | Doctoral thesis, comprehensive summary
Responses to External Cues in Oral Bacteria
Carolina Robertsson
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2023 | Article, review/survey
Applications of Tumor Cells in an In Vitro 3D Environment
Sylwia Hasterok, Anna Gustafsson, Anette Gjörloff Wingren
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2023 | Chapter in book
Formation and Analysis of Mono-species and Polymicrobial Oral Biofilms in Flow-Cell Models
Jessica Neilands, Gunnel Svensäter, Gabriella Boisen, Carolina Robertsson, Claes Wickström, Julia R Davies
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2023 | Article in journal
In vitro effects of undifferentiated callus extracts from Plantago major L, Rhodiola rosea L and Silybum marianum L in normal and malignant human skin cells cells
Anette Gjörloff Wingren, Riyam Ziyad Faik, Anna Holefors, Edina Filecovic, Anna Gustafsson
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2023 | Article in journal
The Apparent Organ-Specificity of Amyloidogenic ApoA-I Variants Is Linked to Tissue-Specific Extracellular Matrix Components
Rita Del Giudice, Mikaela Lindvall, Oktawia Nilsson, Daria Maria Monti, Jens O. Lagerstedt
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2022 | Article in journal
Molecularly Imprinted Polymers Exhibit Low Cytotoxic and Inflammatory Properties in Macrophages In Vitro
Louise Sternbæk, Martha Kimani, Kornelia Gawlitza, Knut Rurack, Birgit Janicke, Kersti Alm, Anette Gjörloff Wingren, Håkan Eriksson
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2021 | Article in journal
Ectopic Bone Tissue Engineering in Mice Using Human Gingiva or Bone Marrow-Derived Stromal/Progenitor Cells in Scaffold-Hydrogel Constructs
S. Shanbhag, C. Kampleitner, S. Mohamed-Ahmed, M. A. Yassin, H. Dongre, D. E. Costea, S. Tangl, Andreas Stavropoulos, A. I. Bolstad, S. Suliman, K. Mustafa
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2021 | Article in journal
Digital holographic microscopy: a noninvasive method to analyze the formation of spheroids
Zahra El-Schich
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Research project
Next generation of cancer models for improved predictivity in drug development – 3D colorectal cell growth with the use of supporting spide...
anette.gjorloff-wingren@mau.se -
Research project
Beneficial effects of vitamins in skin - Towards next generation skin care and 3D skin models
sebastian.bjorklund@mau.se -
Research project
Revert - Targeted therapy for advanced colorectal cancer patients
anette.gjorloff-wingren@mau.se -
Research project
Enzymatic activity in oral biofilms – biotechnological applications and putative predictive biomarkers for oral health and disease
fredrik.leo@mau.se -
Research project
Biobarriers – Health, disorders and healing
johan.engblom@mau.se -
Research project
Detection and sensing of predictive biomarkers for periodontitis
borje.sellergren@mau.se